Making combinations that are hard to complete with standard cards your top priority when using the Joker is an important part of using it wisely. This could entail completing a run or set with the Joker that you couldn't form with the cards you currently havetime slots in your hand. Knowing when it might be better to hold onto the Joker rather than use it right away is another crucial part of using it wisely. The Joker can be a useful tool for creating combinations later in the game, so it's important to think about the situations in which holding onto it instead of using it right away might be a smart strategic move. Effective use of the Joker also requires flexibility and a readiness to modify strategy in response to fresh information that becomes available during gameplay.